Amoxapine

This product is dibenzo oxygen and nitrogen Zhuo tricyclic antidepressants.

Chinese alias oxychloride level; chlorine piperazine oxygen Zhuo

EINECS No. 237-867-1

Sub-sub-type C17H16ClN3O

Molecular volume of 313.78

Dangerous Goods signs Xn: Harmful

Pharmacology:

Pharmacology:

This product is dibenzo oxygen and nitrogen Zhuo tricyclic antidepressants, compared with imipramine, have similar anti-inhibition effect, but rapid onset of cardiac toxicity is low, anticholinergic effects and sedation weak. Product can inhibit the brain synaptic membrane of the NA reuptake (for 5-HT reuptake little influence), resulting in a strong anti-suppression effect with the spirit of excitement. Rapidly and completely absorbed after oral administration, l-2 hours to yield blood concentration in the lung, heart, kidney, brain and spleen tissues of higher concentration. Tissue concentration 10 times higher than plasma concentrations. The hepatic metabolism of 7 - hydroxy 8-hydroxy Jiamosha Jiamosha flat calm, have antidepressant activity, the t1 / 2 were 6.5 hours and 30 hours. Most of the metabolites and glucuronide, and finally discharged from the kidney, a small amount from the feces.

Amoxapine